翟翠,医学博士,讲师。2020年毕业于西安交通大学医学部,获得医学博士学位。2020年7月至2021年8月,曾于陕西省人民医院呼吸与危重症医学一科担任医师。2021年11月至今,任西安医学院生命科学与工程学院 / 基础与转化医学研究所讲师。
主要从事肺动脉高压病因与发病机制研究,重点关注肺动脉高压的代谢组学特征及其在疾病诊断与治疗中的潜在应用。近年来,致力于探索代谢异常与肺动脉高压发生发展之间的内在联系,以期为该疾病的精准诊疗提供新的理论基础与干预靶点。
[1] Zhu Y, Wang X, Yan X, Sun Y, Wang Q, Zhai C. Identification of potential biomarkers associated with mitochondrial oxidative stress in idiopathic pulmonary arterial hypertension via bioinformatic and experimental analysis. Scientific Reports. 2025;16(1):1647.
[2] Zhai C, Feng W, Shi W, Wang J, Zhang Q, Yan X, Wang Q, Li S, Liu L, Pan Y, Zhu Y, Chai L, Li C, Liu P, Chen Y, Li M. Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation. European Journal of Pharmacology. 2020;884:173302.
[3] Zhai C, Shi W, Feng W, Zhu Y, Wang J, Li S, Yan X, Wang Q, Zhang Q, Chai L, Li C, Liu P, Li M. Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation. Life Sciences. 2018;208:87-95.
[4] Zhai C, Li S, Feng W, Shi W, Wang J, Wang Q, Chai L, Zhang Q, Yan X, Li M. Association of interleukin-17a rs2275913 gene polymorphism and asthma risk: a meta-analysis. Archives of Medical Science. 2018;14(6):1204-1211.
[5] Zhai C, Zhang N, Wang J, Cao M, Luan J, Liu H, Zhang Q, Zhu Y, Xue Y, Li S. Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation. Lung. 2022;200(5):619-631.